ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages-2

Abstract

Mes (BP). B. Exposure to ATP is associated with the appearance of numerous double-membrane autophagic vacuoles (AV) within the cell cytoplasm. C. A BCG-infected human macrophage (MDM) following treatment with 3 mM ATP for 30 minutes, the bacteria localize within autophagic vacuoles (AV) with clearly demonstrable inner (double black arrows) and outer (double white arrows) membranes. D. A higher magnification image of a number of mycobacteria contained within the inner and outer membranes of an autophagic vacuole.<p><b>Copyright information:</b></p><p>Taken from "ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages"</p><p>http://www.biomedcentral.com/1471-2172/9/35</p><p>BMC Immunology 2008;9():35-35.</p><p>Published online 15 Jul 2008</p><p>PMCID:PMC2483257.</p><p></p

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