Ionic Liquid-Supported
Aldehyde: A Highly Efficient
Scavenger for Primary Amines
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Abstract
Novel aldehyde-functionalized ionic liquids have been
synthesized
and used as scavengers for primary amines in the synthesis of secondary
amines. The yields of secondary amines are high (82β90%) with
high purity. The advantages of the protocol over that with a polymer-supported
aldehyde scavenger are the shorter reaction time, the homogeneous
reaction medium, the high level of loading of the aldehyde group,
easy monitoring of reaction, and characterization of intermediates