<p>Genes and samples were clustered independently by hierarchical clustering. Rows represent genes, and columns represent samples, which are color-coded by <i>p53</i> status (blue and red correspond to wt-<i>p53</i> and <i>p53</i> mutant, respectively. The color scale is shown at bottom right. Values are expressed as log2-ratios of expression in CRCs with <i>p53</i> mutant phenotypes to that in wt-<i>p53</i> phenotypes. (A & B) Clusters of 35 and 49 genes showing consistent up-regulation and down-regulation in <i>p53</i> mutant phenotypes.</p
