Abstract

<p>(1) Feature Extraction: the information from the beta images were transformed into an input vector. (2) Nested leave one out (LOO) Approach. We employed a nested (3-way) cross-validation, where we first excluded one matched pair of subjects to comprise the test set (test loop in light blue). We then performed a second split (validation loop in dark blue), where we removed 5000 voxels each iteration and repeatedly repartitioned the remaining 15 subject pairs into a validation set (1 pair) and training set (14 pairs) to compute the mean accuracy on the validation set. This procedure (removing voxels and computing mean accuracy) was repeated until all voxels were removed. We then selected the number of voxels that produced maximal accuracy on the validation set before applying it to the test set. The final accuracy was the mean accuracy over all test subjects (outer test loop in light blue). (3) We then generated a map training the GPC with all subjects and removing voxels until we obtained the mean number of voxels.</p

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