We used the predictive probabilities from the classifier at-risk adolescents vs. controls as a score for the at-risk adolescents.

Abstract

<p>An ROC curve was used to evaluate if this score could be used to predict which of at-risk adolescents developed a future mood disorder. Each point on the ROC curve represents a sensitivity/specificity pair corresponding to a particular decision threshold. A test with perfect discrimination has a ROC curve that passes through the upper left corner (100% sensitivity, 100% specificity). The area under the ROC curve (AUC) was 0.78 (p<0.05).</p