Suzuki Coupling of Potassium
Cyclopropyl- and Alkoxymethyltrifluoroborates
with Benzyl Chlorides
- Publication date
- Publisher
Abstract
Efficient Csp<sup>3</sup>–Csp<sup>3</sup> Suzuki
couplings
have been developed with both potassium cyclopropyl- and alkoxymethyltrifluoroborates.
Moderate to good yields have been achieved in the cross-coupling of
potassium cyclopropyltrifluoroborate with benzyl chlorides possessing
electron-donating or electron-withdrawing substituents. Benzyl chloride
was also successfully cross-coupled to potassium alkoxymethyltrifluoroborates
derived from primary, secondary, and tertiary alcohols