Adaptive transfer demonstrates involvement of αA with immune regulation.

Abstract

<p>Inflammatory cell infiltration is a hallmark of the progression in EAU. Note inflammatory cells (arrows) in the vitreous in (a) representing the status of early retina in Rag2−/− mice injected with splenocytes and lymphocytes from αA−/− mice with EAU. Note the relative absence of this infiltration in b, which represents the status of retina in Rag2−/− mice injected with splenocytes and lymphocytes derived from the wild type mice (129Sve) with EAU. PR = Photoreceptors, ONL = Outer nuclear layer, INL = Inner nuclear layer, GCL = Ganglion Cell layer.</p

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