Pre-existing anti-Ad5 capsid neutralizing antibodies reduced immune responses generated by MRKAd5 HIV-1 gag/pol/nef vaccine, especially HIV-specific CD8+ immune responses.

Abstract

<p>Median (25%–75% percentile),</p>*<p>: p<0.05;</p>**<p>: p<0.01,</p>***<p>: p<0.001.</p