<p>(A) Kinetics of kallikrein activation in normal plasma and C1inh-depleted plasma with the addition of 25 µg/ml of OSCS. Kallikrein activity was also determined in (B) normal human plasma and (C) C1inh-depleted plasma with different doses of OSCS. The OSCS dose response was also evaluated with plasma samples treated with antibody-coated bacteria. Experiments were repeated independently twice. Duplicate samples were used in panel A.</p