<p>On days 0, 7, 14, and 21, streptococcal cell wall (SCW) fragments were injected intra-articularly (i.a.) into the knee joint. Joint swelling (ratio of <sup>99 m</sup>Tc uptake in the treated right knee joint to that in the untreated left knee joint) were determined 1 day after every injection (A) and during the chronic phase of the model on day 28 (B; n=6 mice/group). In addition, the inflammatory cell influx (C) on histological slides was quantified on day 28. H&E stained frontal knee sections (original magnification 100×) (D) are shown (n=8 mice/group. Values are the mean ± SEM; ns=non significant, * P<0.05, ** P<0.01, *** P<0.001, by One-way ANOVA.</p
