Continuous-Flow Synthesis
of Monoarylated Acetaldehydes
Using Aryldiazonium Salts
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Abstract
Anilines and ethyl vinyl ether can be used as precursors
for a
process that is the synthetic equivalent of the α-arylation
of acetaldehyde enolate. The reaction manifests a high level of functional
group compatibility, allowing the ready preparation of a number of
synthetically valuable compounds