Switching the Stereoselectivity: (Fullero)Pyrrolidines “a la Carte”

Abstract

Stereodivergent syntheses of <i>cis</i>/<i>trans</i> pyrrolidino­[3,4:1,2]­fullerenes and <i>endo</i>/<i>exo</i> pyrrolidines are reported with high enantioselectivity levels. Fullerenes are revealed as a useful benchmark to develop suitable catalysts to control the stereochemical outcome and to shed light on the mechanism involved in the related 1,3-dipolar cycloaddition