A Highly Active Ruthenium(II)
Pyrazolyl–Pyridyl–Pyrazole Complex Catalyst for Transfer
Hydrogenation of Ketones
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Abstract
Ruthenium(II) complexes bearing a pyrazolyl–pyridyl–pyrazole
ligand were synthesized and exhibited exceptionally high catalytic
activity in the transfer hydrogenation of ketones in refluxing isopropyl
alcohol, reaching final TOFs up to 720 000 h<sup>–1</sup>. The β-NH functionality of the pyrazole arm in the ligand
demonstrated a remarkable acceleration effect on the reaction rate.
The unsymmetrical nature (hemilability) and presence of the convertible
NH group of the ligand is attributed to the high catalytic activity
of the complex catalyst