General expression pattern of Rho GTPases in myeloid cells.

Abstract

<p>The mRNA expression of the Rho GTPases is depicted as the average 2<sup>−ΔΔCt</sup> value per Rho GTPases for the individual cell types and averaged for myeloid cells (upper panel) and for the control cell types, i.e. PBLs, HeLa and neuroblastoma cells (second panel). CD34; CD34<sup>+</sup> cells, iDCs; immature DCs, mDCs (LPS); LPS-matured DCs, mDCs (PGE2); PGE<sub>2</sub>-matured DCs. Expression of the Rho GTPases in each cell type was determined in 2 or 3 different donors or donormixes (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042563#s4" target="_blank">Materials and Methods</a>). The colors mark the expression level. The lower panel shows a ranking of the Rho GTPase expression in myeloid cells and in the control cell types.</p

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