Parallel Microflow Photochemistry: Process Optimization, Scale-up, and Library Synthesis

Abstract

A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of sensitized photoadditions involving 2(5<i>H</i>)-furanones. The reactor allowed for rapid and energy-, time-, and space-efficient sensitizer screening, process optimization, validation, scale-up, and library synthesis