<p>(A) swim-up (Up) sperm samples; (B) swim-down (Dn) sperm samples; (C) whole sperm population at 1 h (Ws 1 h) samples; (D) Box plot representing the inter-individual variability of DNA methylation levels in total CpGs from the swim-up, swim-down and whole sperm population at1h samples. The median value is shown. * corresponds to p value = 0.0213; R2 = Pearson coefficient. The boxes describe the lower quartile (Q1, 25%), median (Q2, 50%) and the upper quartile (Q3, 75%); the whiskers extend 1.5 times the IQR from the box.</p