Diarylheptanoid Sulfates
and Related Compounds from <i>Myrica rubra</i> Bark
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Abstract
Three new diarylheptanoids, myricanol 11-sulfate (<b>1</b>), juglanin B 11-sulfate (<b>2</b>), and myricanone
5-<i>O</i>-(6′-<i>O</i>-galloyl)glucoside
(<b>3</b>), were isolated from the bark of <i>Myrica rubra</i>. Compounds <b>1</b> and <b>2</b> were characterized
as diarylheptanoid sulfates on the basis of spectroscopic analyses.
The antioxidative activities of the fractionated extracts and isolated
compounds were estimated by the oxygen radical absorbance capacity
(ORAC) and superoxide dismutase (SOD)-like activity assays. The major
isolate, myricitrin (<b>4</b>), displayed a high ORAC value
and moderate SOD-like activity (13 198 μmol TE (Trolox
equivalent)/g and IC<sub>50</sub> 127.5 μg/mL, respectively),
which might explain the potent antioxidative activity of this material