Some Norovirus patients have a highly divergent microbiota compared to controls.

Abstract

<p>Principle coordinates analysis showed the community structure relationship between NoV and HMP patients. This ordination was generated using a Yue and Clayton-based distance matrix representing the relative abundance of OTUs in each community at a 3% OTU definition level. The community of each patient is indicated by a symbol. Arrows depict how the top five most frequently detected OTUs influence the location where each patient is represented. A subset of NoV-infected individuals display a highly divergent community characterized by decreased Bacteriodetes and an increased Proteobacteria. The patients circled represent the disrupted group, which are dominated by Proteobacteria. The majority of the elevated Proteobacteria in these patients was from a single OTU of <i>E. coli</i>.</p

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