CTCF and RAD21 are bound within the <i>Lmo2-Caprin1</i> region at sites of chromatin-chromatin interaction.

Abstract

<p>The mouse <i>Lmo2-Caprin1</i> region on chromosome 2 is depicted with chromosome coordinates shown at the top. <i>Lmo2</i> promoters are indicated by red boxes. Distal regulatory element (DRE) homology regions are indicated by black boxes joined by a line to delineate the human enhancer construct used in the generation of transgenic mice. Mouse ENCODE ChIP-Seq data for the cohesin complex member RAD21 and CTCF are shown below DRE. Proximal promoter (pP), distal promoter (dP), murine erythroleukemia cells (MEL differentiated with 2% DMSO).</p