<p>The first time point imaged in each case was approximately two minutes after stretch, allowing sufficient time for stretch-induced cytoskeletal depolymerization to occur. The normalized fibrosity metric measures changes in the total length of features in an image that are within the thickness range of stress fibers (“fibrosity”). These three classes of response were significantly different relative to an unstretched control (B). Each curve represents the average of at least three cells that were imaged at both 5% and 10% stretch; error bars are standard error.</p
