Similar numbers of Iba1-positive microglia are present in PBS- and rhGas6-treated mice.

Abstract

<p>A. Following cuprizone ingestion for 4 weeks an extensive Iba1-positive microglial activation within the corpus callosum is observed. There was significant reduction of Iba1-postive microglia in both PBS- (B), and rhGas6-treated mice (C and D) at 14 days post treatment relative to 4 week cuprizone treated mice (p<0.02). Arrows show Iba1-positive microglia.</p