BoNT/A Hcβtre immunogens induce antibodies that recognize epitopes distinct from those induced by BoNT/A toxoid.

Abstract

<p>Day 40 sera from a subset of rabbits included in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0016532#pone-0016532-g001" target="_blank">Figure 1</a> were tested for the presence of antibodies specific for BoNT/A Hc or BoNT/A toxoid by ELISA. <b>a</b>: serum anti-BoNT/A toxoid IgG titers significantly greater than those induced by all other groups. There were no other significant differences between groups.</p