Overall methylation profiling of three cell types.

Abstract

<p>All methylation sites measured by microarray were used to profile the overall methylation patterns of the three cell types, iPSCs, ESCs, and SCs. A, unsupervised clustering analysis revealed that SCs were separated from PCs (iPSCs and ESCs). In the PCs subgroup, most ESCs were separated from iPSCs. B, Correspondence analysis classified three cell types, SCs, iPSCs, and ESCs. SCs and PCs were separated in first component while most of ESCs and iPSCs were separated in second component. C, iPSCs and ESCs were further classified by correspondence analysis in 3D space. For visualization purposes, only one subset of data was shown here.</p

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