Inflammation-associated gene expression in flow-conditioned endothelial cells.

Abstract

<p>Shown is fold mRNA expression (with respect to static-cultured endothelial cells) of cell adhesion molecules (A) and genes with roles in recruitment of inflammatory cells (B). Results are presented as mean±SEM. An embedded asterisk indicates a significant difference with respect to static controls; an asterisk over a bracket indicates a significant difference between flow groups. Abbreviations: <i>PSGL-1</i>: P-selectin glycoprotein ligand-1; <i>ICAM-1</i>: intercellular adhesion molecule-1; <i>VCAM-1</i>: vascular cell adhesion molecule-1; <i>PECAM-1</i>: platelet-endothelial cell adhesion molecule-1; <i>ALOX5</i>: arachidonate 5-lipoxygenase; <i>PLA2G4C</i>: cytosolic phospholipase A2 gamma; <i>ADAM17</i>: ADAM metallopeptidase domain 17; <i>MCP-1</i>: monocyte chemoattractant protein-1; <i>CX3CL1</i>: fractalkine.</p