<p>(a) Video micrograph of a vesicle aspirated in a glass suction capillary. The principal variables for the determination of the area expansion modulus are indicated: R<sub>V</sub>: vesicle radius, p<sub>in</sub> and p<sub>out</sub>: pressure inside and outside the vesicle, ΔL: length of membrane meniscus inside a glass pipette of internal radius R<sub>p</sub>. Excess membrane tension τ is created by suction such that Δp≠0. (b and c) Histograms of the micromechanical quantities measured in the test system under various experimental conditions. (b) K<sub>s</sub>: expansion modulus (mN/m); (c) τ<sub>r</sub> : tensile breaking strength (mN/m). Caspase-8 was added to a final concentration of 290 nM, tBid to 30 nM and Bid to 50 nM. Fisher’s test were used for statistical analyses of differences for both K<sub>s</sub> and τ<sub>r</sub> measurements (**, p<0.01 and *** p<0.05).</p
