Mo-DCs produce significantly less iNOS during infection with <i>L. mexicana</i> compared to <i>L. major</i>.

Abstract

<p>C57BL/6 mice were infected and ears were processed as above. In addition to staining for surface markers, intracellular staining for iNOS was performed. Percentage (<b>A</b>) or absolute number (<b>B</b>) of iNOS-producing cells in the ear of naïve or infected mice on day 14. Cells are previously gated on live, singlets that are CD11b^hi CD11c⁺. The results expressed are the mean percentage (± SD for FACS plots) or the mean number of cells (± SE for the bar graph) of 3 mice per group. The results are representative of two experiments. * significantly lower (p<0.05) compared to <i>L. major</i> infected mice.</p