Architecture of gene encoding the lethal toxin from Australian funnel-web spiders.

Abstract

<p>Alignment of the cDNA and gDNA sequences obtained for δ-hexatoxin-Hi1a. The nucleotide sequences are identical except at a single position (T versus C, highlighted in grey) that does not alter the encoded protein sequence. The stop codon is denoted by an asterisk. A schematic of the toxin precursor showing the signal peptide, propeptide, mature toxin, and 3’ untranslated region in yellow, blue, purple and white, respectively, is shown above the sequences. The protein sequence (i.e., a translation of the cDNA/gDNA) is shown sandwiched between the cDNA and gDNA sequences.</p

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