<p>(A) VEGF and FGF-2 levels in tumors specimens and (B) in A431 cells treated with or without IL-1β (10 ng/ml, 18 h) in presence/absence of AF3485 (10 µM). *P<0.05, **P<0.01. ADU = arbitrary density unit ± standard deviation. (C) Pseudocapillary formation of EC exposed for 16 h to conditioned media from A431 treated with 0.1% FBS (panel a: control), IL-1β (panel b: 10 ng/ml, 18 h), AF3485 (panel c: 10 µM, 24 h), IL-1β + AF3485 (panel d: 24 h) *P<0.01 vs. cont, #p<0.01 vs. IL-1β. (D) VEGF and FGF-2 expression in A431 cells co-cultured with NIH-3T3 for 24 h.</p
