Expression of Nkx2.5 in the heart tissue of diabetic mice (DM).

Abstract

<p>(A) Immunoblotting analysis of Nkx2.5 and <i>O</i>-GlycNAcylated proteins in the heart tissue of DM intraperitoneally injected with streptozotocine (180 mg/kg body weight). (B) Graphs showed relative <i>O</i>-GlcNAc (left) and Nkx2.5 (right) levels normalized to the tubulin levels in DM and control. Nkx2.5 protein in diabetic heart of mice was significantly decreased. <i>O</i>-GlcNAcylation and Nkx2.5 protein levels were compared in DM <i>vs</i> control. All values are presented as the mean±standard error of three independent experiments. *<i>p</i><0.05 DM vs. control.</p

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