<p>Pc-infected SCID mice were immunologically reconstituted and then treated with PBS or SSZ beginning at day 1 post-reconstitution. (A and B) Body weight and respiratory rates were monitored non-invasively. (C, D, E) Dynamic lung compliance, lung resistance and BAL albumin content were measured at 13, 18, and 25 days post-reconstitution. Values are mean ±1 standard error measurement (SEM) (n≥15 for day 13, n≥37 for day 18, and n≥15 for day 25). ** and #, P<0.05 as compared to uninfected mice at the same time point. *, P<0.05 as compared to SSZ treated mice at the same time point. Mean represents combined data from eight independent experiments.</p
