Effect of elevated glycerol levels on the properties of age-induced Q35::YFP aggregates.

Abstract

<p><i>A:</i> Fluorescence micrographs of aggregate morphology in body wall muscle cells of control worms, worms acclimated to 200 mM NaCl and <i>osm-11</i> mutant animals. Images were taken from 7-day old adult worms. Scale bar is 10 µm. <i>B:</i> Time course of bleaching and fluorescence recovery in aggregates of young (4-day old) and old (10-day old) adult control, acclimated and <i>osm-11</i> worms (<i>n</i> = 3). <i>C:</i> Aggregate toxicity in control, acclimated and <i>osm-11</i> worms. Toxicity is measured as reductions in motility, which is mediated by body wall muscle cells. (<i>n</i> = 5–12).</p

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