<p>Analysis of the first and second phase of Tibialis Anterior (TA) reflex temporal summation in naïve animals (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026107#pone-0026107-g004" target="_blank">Fig. 4A</a>) and those with SCI 28 days after T9 spinal contusion (Cont) revealed that the synergistic phasic inhibitory effect of Albumin-Oleic acid produced with the high-frequency electrical conditioning stimulation when normalized to the first phase of the pre-conditioned response was present during both the early and late phases of temporal summation (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026107#pone-0026107-g004" target="_blank">Fig. 4C</a>), but not in the group treated with Saline (Sal, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026107#pone-0026107-g004" target="_blank">Fig. 4B</a>) or in naïve animals (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026107#pone-0026107-g004" target="_blank">Fig. 4A</a>). Furthermore activation of phasic inhibition of absolute integrated TA reflex activity measured during both phases of temporal summation revealed that Alb-OA treatment significantly inhibited nociceptive activity to below the normal value observed in naïve animals during the early phase (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026107#pone-0026107-g004" target="_blank">Fig. 4D</a>). Statistical analysis was performed with a one-way ANOVA supported by a post-hoc Bonferroni test (* - p<0.05; ** - p<0.01, ***-p<0.001).</p
