Mean arterial pressure in response to chronic intramedullary blockade of ET-B receptors.

Abstract

<p>Chronic intramedullary blockade of ET-B receptors causes a slight increase in MAP in rats on a normal salt diet (112.8±2.4 in vehicle vs. 120.7±9.3). However, rats placed on high salt diet had a much greater elevation in MAP in response to IM ET-B blockade (123.7±3.2 vs. 164.2±7.1). * denotes p<.05 vs. all other groups.</p