<p>Human volunteers were sham-irradiated or exposed to UVB 5 times weekly for 4 weeks. Biopsies were taken and GAGs were visualized using Hale's stain. Collagen stains red, cytoplasm stains yellow, and GAGs stain blue in (a) control skin and (b) UVB-irradiated skin. The images in this figure are of tissue from the same patient. The GAG stain intensity was quantified using ImagePro version 3 and graphed (c). Sham skin is represented by open bars and UVB-irradiated skin by solid bars. (size bars = 62.5 µm, ***p<.001 versus sham, n = 5).</p
