The RsW50 of regulatory spleen cells is decreased by enriching for CD8<sup>+</sup> regulatory spleen cells.

Abstract

<p>The footpads of mice immunized with TNP-BSA and CFA 9 days previously received id CD8<sup>+</sup> cells or unseparated AC-SPL cells prepared as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022496#pone-0022496-g001" target="_blank">Fig. 1</a> immediately after the footpad was challenged with epicutaneous PCl. Swelling was measured 24 hr later. The data is pooled from two separate experiments with six mice /group. NAÏVE: non-immunized mice, IMM: immunized mice that did not receive regulatory spleen cells, CD8<sup>+</sup>: immunized mice that received CD8<sup>+</sup> regulatory spleen cells. p<0.01. Straight lines were generated by curve fit software.</p

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