GW4064 treatment inhibited transdifferentiation of HSCs.

Abstract

<p>Freshly isolated rat HSCs were cultured for 7 days in 10% FCS alone (control) or 10% FCS medium containing 1 µmol/L GW4064. The expression of α-SMA mRNA (A) and protein (B) was examined by real-time RT-PCR and immunofluorescence staining, respectively. Data are mean ±SE of 6 experiments. *<i>P</i><.001 vs. control cells.</p