'Royal College of Obstetricians & Gynaecologists (RCOG)'
Doi
Abstract
Diethylzinc mediates the asymmetric allylation of aldehydes through Umpolung of a π-allyl palladium complex. An investigation of the palladium source and the chiral monophosphane ligands have shown that the leaving group has a dramatic effect on the enantioselectivity of the reaction. The procedure furnished products in satisfactory yields and up to 70% ee