Cerebellar tremor with anti-GAD antibodies

Abstract

Glutamic acid decarboxylase (GAD) catalyzes the conversion of glutamic acid to gamma-aminobutyric acid (GABA). Autoantibodies directed against GAD (anti-GAD-Ab) have been described in a few patients with progressive cerebellar ataxia, however, the occurrence of a definite cerebellar tremor has not been documented