Synthesis of stereodefined 1-aryl(heteroaryl) substituted 1,2-bis(2-bromopyridin-3-yl)ethenes by selective tandem Suzuki-Miyaura
Cross-coupling reactions
In this communication we show the preparation of
stereodefined trisubstituted alkenes 2 can be achieved by sequential selective Suzuki-Miyaura
reactions of 2-bromo-3-(2,2-dibromovinyl)pyridines. The potentiality of this
strategy to obtain 5-aryl-1,10-phenanthrolines is also demonstrated
