Although Peyer's patches (PPs) and the enteric nervous system (ENS) play a key role in early sheep scrapie
pathogenesis, little is known on the kinetics of ENS plexuses colonization.
This study was aimed at quali-quantitatively evaluating ileal PP innervation in 29 Sarda breed ovines (12 scrapie-free, 2
months-old lambs, 4 ARQ/ARQ, 4 ARR/ARQ and 4 ARR/ARR, respectively; 12 scrapie-free, 2-4 years-old sheep, 3
ARQ/ARQ, 7 ARR/ARQ and 2 ARR/ARR, respectively; 5 ARQ/ARQ scrapie-affected sheep)
