Additional file 3: Table S2. of Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3
GO analysis of all 7 sets of genes - Up- and Down- regulated genes upon treatment by Nutlin-3 in two concentrations 5 μM and 30 μM of Nutlin-3 (p-value< 0.05, LogFC> 0.58 (which corresponds to FC > 1.5) for up-regulated and LogFC<− 0.58 for down-regulated genes). Parameter Sum_Logpval sums up logarithms of p-values for one GO term in different conditions of treatment. It allows to sort GO terms according to their total significance in all conditions. (XLSX 334 kb
