Inhibition analysis of IRES-mediated translation by aptamers

Abstract

<p><b>Copyright information:</b></p><p>Taken from "A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III–IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId"</p><p>Nucleic Acids Research 2005;33(2):683-692.</p><p>Published online 28 Jan 2005</p><p>PMCID:PMC548359.</p><p>© The Author 2005. Published by Oxford University Press. All rights reserved</p> Luciferase activity in the absence of an aptamer was used as a control (100%). Values represent results from at least three independent experiments. , and are equivalent to the groups in