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Choledochal duct obstruction in human by Fasciola hepatica

Abstract

Fascioliasis is a herbivorous parasitic infection that can be transmitted to humans. Human cases are increasingly reported from different countries. In Iran, more of human Fascioliasis has reported from Guilan province but in contrast Ardabil as a province is not known as endemic area. A 75 years old Iranian woman resident in Germi city, Ardabil province, complained with abdominal pain (right upper quadrant), fever, Icterus, nausea, dark urine and colorless stool referred to Emam Khomeini hospital. After blood examination and sonography of internal organs, the patient was operated for cholecystectomy. Blood examination showed increased WBC, levels of liver enzymes activity and bilirubin (total & direct), in contrast decreased hemoglobin and abnormality in coagulation tests. Sonograghy of liver identified common bile duct dilation and high echogenicity in distal part of choledochal duct. In cholecystectomy, the flat leaf shape worms were obtained from site of obstruction and morphological evaluation confirmed Fasciola hepatica as cause of choledochal duct obstruction. Early diagnosis of fascioliasis can prevent from complex and dangerous complications. Considering to reported human cases from Ardabil province, epidemiological studies are needed for determination of prevalence of human infections in Ardabil

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