AGE-modification of laminin results in disorganization actin cytoskeleton in rMC-1 cells.

Abstract

<p>rMC-1 cells were propagated on AGE-modified laminin and stained for the phalloidin antibodies. The untreated cells exhibited continuous trans cytoplasmic actin filaments (white arrow). The treatment of rMC-1 cells on AGE-modified laminin resulted in disorganization of actin skeleton and the actin was mostly observed in clumps in the cytoplasm (yellow arrow), n = 3.</p