Background & Aim: Bacterial vaginosis is characterized by an
imbalance in vaginal natural discharges due to an overgrowth of
anaerobic bacteria as well as a concomitant decrease in the number of
lactobacilli and increase in vaginal PH to more than 4.5. Bacterial
vaginosis increases the risk of pelvic inflammatory disease, postoperative infection following hysterectomy, cervix abnormal cytology and preterm birth. Microbial resistance and a growing tendency to move toward "natural therapies" have led to increase interests in nonantibiotic treatments for bacterial vaginosis. This study aimed to
compare the effects of Lactobacillus acidophilus suppository and
Metronidazol vaginal tablet on treatment of bacterial vaginosis.
Methods & Materials: In a double-blind, paralled randomized clinical
trial, 40 out of 300 participants were included in the study from an outpatientprivate gynaecology clinic in Tabriz, Iran. The participants
were randomly allocated to two treatment groups of Lactobacilli
suppository and Metronidazol vaginal tablet.
Results: The cure rate for the Metronidazol group and the Lactobacilli
supository group were 100 and 75 per cents, respectively.
Conclusion: According to the results of this study, Metronidazol was
more effective in treatment of bacterial vaginosis than the Lactobacilli
suppository. A combination of these medications are suggested for
resistant to treatment cases
