Abstract

<p>Urodynamic studies showing three different scenarios of overactive bladder found on CZS patients, all with high-risk urodynamic indicators known to cause progressive urinary system damage. A (case 1): Bladder behavior is normal at the beginning but a series of uninhibited detrusor contractions raises the bladder pressure during 2/3 of the filing phase. B (case 2): A very high and sustained inhibited detrusor contraction and a concomitant increased sphincter activity (detrusor-sphincter dyssynergia) raises the intravesical pressure up to 100 cm H<sub>2</sub>0. The leak point pressure is equally dangerously high (110 cm H<sub>2</sub>0). C (case 3): The repeated inhibited detrusor contractions starting at the very beginning of the filing phase, always followed by leak, severely reduces the bladder capacity.</p

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