Figures S1 and S2; Table S1 from Inhibitors of both the <i>N</i>-methyl lysyl- and arginyl- demethylase activities of the JmjC oxygenases

Abstract

Time course assays using LC-MS showing the extent of KDM (A) or RDM (B) demethylation.; Comparison of the KDM and RDM activities of KDM4E.; Kinetic parameters (KM, kcat and kcat/ KM)) for substrates and 2O