A total of 17 probe sites where increased placental CpG methylation predicted more severe cognitive impairment at ten years of age.

Abstract

<p>These sites corresponded to 16 unique genes. The model represents the increase in the odds of moderate or severe cognitive impairment at age ten for every one percent increase in methylation at the probe site. Significance was defined as a p-value < 0.05 in a logistic regression model.</p