Background and objective Warts are common dermatological disorder which are dfficult to treat and usually relapse.In this study the effhcacy of topical 5-FU was compared with conventional cryotherapy in treatment of plantar warts.
Methods: In a cilinical trial study,50 patients cilinically diagnosed as warts were divided in to two groups.25 patients were treated with topical 5-FU while the other 25 were treated with cryotherapy.After treatment patient were followed for 6 months from the viewpoints of treatment coplication,efficacy and relapse rate.
Results: It was observed that treating period in cryotherapy was short but 5-FU therapy needed longer time.Initially in 5-FU group 52% of patient had good response,36% moderate response and in 12% no response was obseved there is no significant difference in view of sex in this group and in cryotherapy group 60% of patients had good response,28% moderate response and in 12% no resonse was observed like wise there was no significant differrnce in term of gender.In response to therapy there was no difference between two groups after 6 months followed up relapse rate was 18% in cryotherapy patients and only 8% in 5- FU group which wasnt statistically meaningful and no difference was observed between two groups .
Conclusion: The results indicated that course of treatment was short in cryotherapy than the topical 5-FU but the relapse rate didnt have any difference between two groups.The only significant difference was pain in which 5-FU was painless but cryotherapy was painful
