The evaluation of correlation between Pseudoexfoliation of pupil and increased intraocular pressure or glaucoma in patients referred to ophthalmology clinic of Ardabil Alavi hospital
Introduction : Purpose : To evaluate the pseudoexfoliation syndrome and its associations with elevation of IOP/Glaucoma this study was designed and performed in Ardabil Alavi hospital.
Methods : This was a hospital-based, cohort study in Ardabil Alavi hospital from Farvardin 1387 to Aban 1388. Only patients of aged 50 and older referred to Alavi clinic of ophthalmology were examined to find the PEX depositions. PEX was diagnosed on slit lamp biomicroscopy by the presence of white dandruff-like material in the pupillary margin or other sites of one or both eyes. These patients was known as “case group”, another group was prepared with the same age subgroups of case groups and was known as “control group”. There was 72 patients in both groups. All patients underwent a comprehensive ophthalmic evaluation. Visual acuity, refraction, Goldmann applanation tonometry, gonioscopy, slit lamp examination and dilated pupil fundus examination was performed.
Results : Out of 144 eyes of case group, 112 (77.77%) had PEX depositions. There was a significant increase in number of PEX involved eyes with age. In this study the frequency of disease in men was higher than women (46 (63.9%) men, 26 (36.1%) women). Out of 72 patients, 40 (55.5%) patients were bilaterally and 32 (44.5%) patients were unilaterally involved. The mean of IOP in PEX involved eyes was 17.94±8.88 and 14.51±2.90 in non PEX involved eyes. The frequency of cortical cataract was higher than other forms.
Conclusion : PEX is an important risk factor for increased IOP and glaucoma in our area and must be considered a lot. Patients with this risk factor must undergo frequent IOP measurement
